Himalaya Reosto
Benefits of Reosto: Herbal Remedy for Post Menopausal Osteoporosis, Senile Osteoporosis, Bone Fractures
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Reosto is a unique complex herbal formula that helps support bone metabolism and maintain bone density. It helps to slow bone loss and reduce the incidence of fractures. Reosto being a natural source of Calcium, eliminates the risk of abnormally high calcium and Vitamin D levels in blood, thereby helps preventing formation of calcium stones in the urinary tract. The presence of phytoestrogens helps in modulating the synthesis and utilization of various hormones to restore the hormonal balance without any side effects.
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Himalaya Reosto
60 Tablets per Bottle
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3 Bottles
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6 Bottles
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12 Bottles
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Indications for using Reosto
Reosto is useful for the treatment of:
- 1. Osteoporosis:
a. Senile osteoporosis
b. Postmenopausal osteoporosis
- 2. Prolonged immobilization following multiple or complex fractures, or surgery for multiple fractures
Benefits of Reosto
- Reosto supports calcium metabolism.
- Reosto helps build and maintain healthy bones.
- Reosto provides a natural source of easily assimilable calcium and vitamin D.
- Reosto supports the microstructure of the bone tissue.
- Reosto has beneficial effects in osteoporosis by early restoration of the bone mass and in accompanying changes in microstructure of the bone.
- Reosto improves the secretion of hormones like estrogen and progesterone, which are drastically reduced in the postmenopausal phase.
- Reosto reverses hypogonadism and osteoporosis induced by long term administration of steroids in chronic diseases like bronchial asthma, rheumatoid arthritis and skin disorders.
Reosto Ingredients (Per Tablet):
- Arjuna (Terminalia arjuna) 45mg
- Guggul (Commiphora wightii) 235mg
- Ashvagandha (Withania Somnifera) 45mg
- Country mallow / Bala / (Sida cordifolia) 45mg
- Rasna (Vanda roxburghii) 50mg
- Godanti Bhasma (Natural Calcium) 120mg
(Godanti Bhasma is a natural form of calcium that helps maintain healthy bone structure)
- Kukkutandatvak bhasma / Hen's Egg Shell Calx 35mg
(Kukkutandatvak bhasma is a rich source of
natural calcium, which helps in healthy bone formation, improves
bone mineral density, relieves bone and joint pains, and possesses
anti-inflammatory property.)
Directions for taking Reosto
Take 2 Tablets twice daily after meals.
Reosto Side Effects:
Reosto is not known to have any side effects if taken as per the prescribed dosage
Reosto from Himalaya Herbals
Reosto is from the renowned Himalaya Herbals brand endorsed by over 250,000 doctors worldwide and used by customers in over 60 countries. Himalaya Herbals products have been researched clinically and standardized to guarantee bioequivalence. Bioequivalence refers to ensuring that the product on the market is equivalent to the one on which clinical trials were successfully conducted. Himalaya Herbal Healthcare uses chromatographic fingerprinting, one of the most sophisticated standardization techniques, to ensure consistent quality and performance
Research and Clinical Studies on Reosto:
There have been several studies conducted on Reosto. The following is one such study published in 2005
Evaluation of the Efficacy and Safety of Reosto in Postmenopausal
Osteoporosis: A Prospective, Randomized, Placebo-Controlled, Double
Blind, Phase III Clinical Trial
Dr. Deepti Dongaonkar, MD, DGO
Professor, Department of Obstetrics & Gynaecology,
Dr. Rajeev Mehta, MD (Radiology)
Hon. Professor, Department of Radiology
Grant Medical College and Sir JJ Group of Hospital, Mumbai, India
Dr. Kolhapure, S.A.* MD
Senior Medical Advisor, R&D Center, The Himalaya Drug Company, Bangalore, India.
[*Corresponding author]
Obst. & Gynae. Today 2005; X(7), 362-367
ABSTRACT
The current management of postmenopausal
osteoporosis (PMO) includes the use of estrogenic
compounds, SERMs, bisphosphonates, calcitonin,
and PTH; however, the associated adverse effects
limit their long-term usage. Recently,
phytoestrogens have been shown to be beneficial
in the management of Postmenopausal osteoporosis. Reosto is a
polyherbal formulation and is a rich source of
phytoestrogens and calcium, and this study was
planned to evaluate the efficacy and safety of
Reosto in the management of Postmenopausal osteoporosis.
The study was a prospective, randomized, double
blind, placebo-controlled, phase III clinical trial,
conducted as per the ethical guidelines of Good Clinical Practice.
One hundred and five healthy women, with
natural or surgical menopause, who had amenorrhea in the preceding 6 months were included
in the study. All women who were consuming any drug, which is known to affect bone
metabolism, those women suffering from endometrial polyps or hyperplasia or other estrogendependent
tumors were excluded from the study. At the randomization visit, a detailed
medical history was obtained from all the enrolled women. Subsequently, all women
underwent a thorough systemic and gynecological examination, routine and bone-specific
biochemical investigations. All women underwent a baseline Bone mineral density examination using DEXA.
All women were randomized in Reosto and placebo groups, and both the groups were advised
to consume the respective medications in dose of two tablets twice daily, orally, for 6 months.
All the enrolled women were monitored at monthly intervals for 6 months, for any reported or
observed adverse effects. The predefined primary efficacy end points were improvement in
the Bone mineral density score and bone-specific biochemical parameters. The predefined secondary safety
end points were incidence of short- and long-term adverse events, and overall patient
compliance to the drug treatment. Statistical analysis was done according to intent-to-treat
principles.
Out of the 105 enrolled women, 11 women had normal Bone mineral density, and 16 women were lost to
follow-up and the data of 78 women (39 from each group) was considered for statistical
analysis.
This study observed a significant increase in the T-score and Bone mineral density of lumbar spine, femur
neck, and hip, in the Reosto group (which indicate the desirable remineralization of
osteoporotic bones). There was also a significant increase in serum calcium and serum
phosphorus, and a significant decrease in serum alkaline phosphatase levels, in the Reosto
group (which indicates the beneficial changes in the biochemical bone markers). Also, there
were no clinically significant changes in any of the hematological parameters, nor was there
any clinically significant adverse reaction, and the overall compliance to the treatment was
excellent (which reflects the short- and long-term safety of Reosto). Therefore it may be
concluded that the treatment with Reosto is effective and safe in the management of Postmenopausal osteoporosis.
ABBREVIATIONS
BMD : Bone mineral density
CVD : Cardiovascular disease
DEXA : Dual energy X-ray absorptiometry
ER : Estrogen receptor
ERT : Estrogen replacement therapy
GCP : Good Clinical Practice
HRT : Hormone replacement therapy
HS : Highly significant
LDL : Low density lipoprotein
NO : Nitric oxide
NS : Nonsignificant
OP : Osteoporosis
PMO : Postmenopausal osteoporosis
PTH : Parathyroid hormone
ROS : Reactive oxygen species
S : Significant
SD : Standard deviation
SERM : Selective estrogen receptor modulator
More Information on Reosto Research and Clinical Studies
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