Liv-52® also known as LiverCare® is a herbal formulation that is the World's #1 Liver Support Formula. Liv52 has been validated by 276 clinical trials and research studies.

Liv.52 maintains the functional efficiency of the liver. It detoxifies and protects liver cells from harmful toxins and supports the liver's ability to regenerate itself . Liv.52 promotes optimum liver function and as a daily health supplement, it helps to improve appetite and the digestion and assimilation processes.

Liv.52 also supports the liver’s function when challenged by toxins not just in our food, water and air, but also increased consumption of protein and prohormones. Liv 52 does not interfere with medications when taken together which is a benefit it has over Milk Thistle.

Liv.52 facilitates rapid elimination of acetaldehyde, the toxic intermediate metabolite of alcohol metabolism, and detoxifies liver cells

Benefits of Liv52

• Liv 52 improves the functional efficiency of the liver.
• Liv 52 promotes detoxification and protection from harmful food and medication toxins.
• Liv 52 helps to maintain healthy levels of liver enzymes.
• Liv 52 helps in absorption and digestion.
• Liv 52 helps in the liver's ability of regenerating itself.
• Liv 52 is useful during convalescence.
• Liv 52 supports the liver's normal ability to burn fat.
• Liv 52 helps support the body's metabolic process.
• Liv 52 helps to support a healthy appetite.
• Liv 52 supports the regeneration of liver cells.
• Liv 52 helps to support the body's immune response.
• Along with the liver, Liv 52 also supports health of the kidneys.

Liv52 Packaging

Directions for taking Liv 52

2 - 3 tablets to be taken three times a day or as prescribed by your physician.

To be taken with water after meals.

Liv52 / Livercare herbs properties & action

The herbs in Liv.52 have been selected due to their well known ayurvedic properties that are beneficial for the liver and for overall well being.

Capers (Capparis spinosa) are well known to improve the functional efficiency of the liver and protect and stimulate the liver. Capers have high quantities of rutin and quercetin which are bioflavonoids. Rutin is considered very beneficial as an anti-oxidant and stimulant and helps promote absorption of nutrients while quercetin has anti-bacterial properties. They also help to support the body's inflammation response. Capers also contain nutrients like Vitamin A, Vitamin k, Niacin, Riboflavin, Calcium, Iron and Copper.

In a 2017 study published in the Advanced Pharmaceutical Bulletin, a 12 week randomized double-blind study was conducted on 44 non-alcoholic fatty liver disease (NAFLD) patients. Anthropometric measures, grade of fatty liver, serum lipoproteins and liver enzymes were measured. Weight and BMI were found to be significantly reduced in the group which was given capers. Serum ALT and AST were highly reduced ⁴

Capers

Wild Chicory (Cichorium intybus) is also known as a powerful hepatic stimulant which increases bile secretion and promotes digestion. Wild chicory has even been referenced in ancient Greek writings and was called "Friend of the Liver" by Galenus on account of its stimulating effect on the liver. It has been used in traditional herbal preparations for removal of excess internal mucus as well as for gallstones.

A study published in the Food and Chemical Toxicology journal showed the ameliorating effects of chicory on rats. Chicory extract helped to reduce hepatoxicity and reduce the levels of bilirubin and biochemical markers aspartate aminotransferase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP) and gamma-glutamyl transpeptidase (GGTP). It also helped reduce oxidative stress.⁵

Wild Chicory Flowers

Black Nightshade (Solanum nigrum) – protects the liver from toxicity induced by drugs. It is considered a detoxicant. It is a plant that is found and used around the world both as a herb and as a food. In traditional herbal use, the juice has been used in cases of liver and spleen enlargement as well as when the liver gets scarred by alcoholism and liver tissue damage by other causes. It is also used for skin conditions.

In a study on rats published in the Biological Trace Elements Research journal, it was found that this herb helped to protect the liver from the effects of cadmium chloride toxicity. It helped reduce lipid peroxidation ( which is the oxidative degration of lipids causing cell damage). It also had beneficial effects on the anti-oxidant system of the liver.⁸

Black Nightshade plant & berries

Arjuna (Terminalia arjuna) – helps to protect against toxins and is a tonic for the heart and liver. It also regulates hepatic cholesterol biosynthesis. The bark of Arjuna helps to protect our DNA.

It is considered very benefical as a cardiac protective ⁹ and also has a protective effect on the liver when it is subjected to medications, alcohol and other factors that affect the liver.

Negro Coffee (Cassia occidentalis) promotes detoxification of the liver and helps in promoting digestion. It promotes regularity of bowel movements and has a cleansing and diuretic effect.

A study on rats showed that extract of Cassia occidentalis leaves had a positive effect on kidney function and urine excretion. It was also found to have anti-oxidant properties ¹⁰

Negro Coffee plant

Yarrow (Achillea millefolium) – helps to improve appetite. It has also been traditionally used to stop blood loss. It has been referred to ancient literature when Achilles used it to stop bleeding on his soldiers. In traditional ayurvedic remedies it has also been used for liver conditions, gallbladder conditions, urinary condtions, issues with internal organs and stomach conditions.

Known as "mil-folhas" in Brazil, this herb is widely used in Brazilian folk medicine for heart and kidney conditions. Its traditionally known effects include its diuretic and hypotensive actions. In a study on rats published in the Journal of Ethnopharmacology, it was found that an extract of this herb increases urinary output. This was attributed to the activation of bradykinin B2 receptors and the activity of cyclooxygenases. Bradykinin B2 receptors help in reducing DNA damage, apoptosis, morphological and functional kidney changes ¹¹

Yarrow plant

Tamarisk (Tamarix gallica) - Tamarisk has been used in traditional Indian medicine for liver conditions and kidney conditions. It is said to stimulate the liver and improve digestion. There is a mention in the Bible that Abraham planted Tamarisk trees.

In a study published in the Journal of Enzyme Inhibition and Medicinal Chemistry it was found that Tamarix gallica, a hepatic stimulant and tonic, inhibited hepatic oxidative stress, toxicity and early tumor promotion response in male Wistar rats.¹²

Mandur Bhasma or Ferric Oxide Calx - This is an ayurvedic mineral preparation made from Iron oxide. In Ayurveda it has traditionally been used during conditions of reduced red blood cells, yellowing of skin, loss of appetite and injuries. It is believed to improve strength and the body's natural immunity.

Bhringaraja (Eclipta alba) - This herb has been traditionally used in Ayurvedic remedies for hepatic protection. It has been used in traditional medicines for liver cirrhosis and infections. Bhringaraja is said to have a positive effect on liver cell regeneration.

Punarnava (Boerhavia diffusa) - Punarnava literally means "to make new again". It is considered a great rejuvenator for the liver and kidneys. It is a diuretic herb that helps to flush fluids. It supports the healthy functioning of the liver, kidneys and urinary tract.

Bhumyaamlaki (Phyllanthus amarus) - This herb is considered to be rich in antioxidants and is considered beneficial in traditional ayurvedic medicine in cases of liver tissue damage.

Guduchi (Tinospora cordifolia)- Guduchi which is also known as "amrita" or "divine nectar" supports the effectiveness of protective white blood cells. It supports the body's immune responses and helps in recovery.

Daruharidra (Berberis aristata) - Also known as tree turmeric it has been used in traditional Ayurvedic remedies for skin conditions, for urinary tract conditions, for healing and for conditions associated with joints and muscles.

Mulaka (Raphanus raphanistrum subsp. sativus) - Mulaka or Radish is considered a natural diuretic and helps in flushing urinary calculi and promotes urinary tract health. In traditional Ayurveda it is also considered beneficial for liver and spleen conditions as well as ascites. It is supposed to relieve toxicity and promotes absorption.

Amalaki (Emblica officinalis) - Amalaki or Indian gooseberry is considered very beneficial to remove toxins. It is a rejuvenative that helps in retaining youthfulness and supports the body's immune system. It has diuretic, astringent and tonic properties.

Chitraka (Plumbago zeylanica) - Chitraka herb in Ayurveda is considered a digestive and carminative herb. It helps to improve digestion, absorption and assimilation of food and relieves intestinal cramping. It is also considered beneficial in improving flow of bile in the liver. This herb is heat producing and is said to balance Vata and Kapha doshas

Vidanga (Emblica ribes) - This heating herb is primarily used in Ayurveda to remove intestinal worm infestation. It is considered to have anti-microbial and anti-parasitic properties. Removing intestinal worms allows proper assimilation of food. It is also traditionally used to ease bowel movements, relieve abdominal cramps and improve digestion.

Haritaki (Terminalia chebula) - This herb has a cleansing laxative effect. By its cleansing action, it helps to remove stagnant particles in the bowels which benefits the colon, liver and kidneys.

Parpata (Fumaria officinalis) - It is considered beneficial for the liver and spleen. It helps to purify blood and is considered an appetiser and restorative.

Liv.52 Side Effects

There are no known side effects when Liv 52 is taken as per the prescribed dosage.

Liv.52 Drug Interactions

There are no known drug interactions for Liv 52 when taken as per the prescribed dosage. In India Liv.52 is often recommended to be taken when other medicines are prescribed as it helps to mitigate harmful side effects on the liver and kidneys.

Liv52 / Livercare from Himalaya Herbals

Liv52 / LiverCare is from the renowned Himalaya Herbals brand endorsed by over 250,000 doctors worldwide and used by customers in over 60 countries. Liv-52 was introduced in 1955 by Himalaya Herbal Healthcare. Since then, it has been sold worldwide and is recognized by thousands of health professionals as one of the most effective liver formulas, with beneficial effects reported in over 300 studies. Himalaya Herbals products have been researched clinically and standardized to guarantee bioequivalence. Bioequivalence refers to ensuring that the product on the market is equivalent to the one on which clinical trials were successfully conducted. Himalaya Herbal Healthcare uses chromatographic fingerprinting, one of the most sophisticated standardization techniques, to ensure consistent quality and performance

Liv52 News

Top selling drug in India

According to figures available for July 2007, Liv.52 achieved the highest sales by value and the top selling drug in India beating chemical based allopathic medicines. Liv.52 had sales that exceeded Corex, Phensedyl and Novartis which are best selling medicines of pharmaceutical companies like Pfizer.

Approved as a herbal liver medicine

Himalaya's Liv-52 has been approved as an herbal drug for liver in Switzerland by its FDA equivalent. It is believed to be the first multi-herb remedy granted regulatory approval as a drug, which is an outstanding feat for an herbal product.

Highest selling liver supplement in the World

Liv-52 is the the highest selling liver supplement in the world with more than 2 billion tablets sold every year.

Liv52 / Livercare Research

The benefits of Liv 52 for maintaining a healthy liver have been clinically researched and documented in various scientific and medical journals.

Prominent mention in "Healing Hepatitis Naturally"

Liv.52 has been given extensive coverage in the publications "Healing Hepatitis Naturally" in which leading US health experts discuss scientifically proven natural medicines that treat hepatitis. It has been discussed in 38 pages of this book.

ABC Clinical Guide to Herbs

In publication by the American Botanical Council (ABC) called the ABC Clinical Guide to Herbs, Liv 52 is one of the 13 herbal formulas that have been mentioned.


5 Major Liv 52 Benefits Infographic

Liv 52 Frequently Asked Questions

Can I take Liv 52 even if I don't have any liver damage?

Yes. Liv-52 is a liver tonic and also a general health tonic. It maintains health of the liver and kidneys and detoxifies the body.

Why is Liv 52 recommended with Punarnava?

Punarnava helps regenerate cells of the liver and kidneys. Liv 52 helps to detoxify and supports liver and kidney functions. Punarnava and Liv 52 are complementary ayurvedic products and help boost each other's benefits. Punarnava is one of the herbs already included in Liv52. Many people take it additionally with Liv52.

Does Liv 52 increase hunger?

Liv.52 helps to increase appetite. It is therefore particularly useful for those who are sick or are recovering from an illness. By improving appetite and increasing absorption of nutrients it helps to regain strength.

Why is Liv-52 taken by bodybuilders?

Bodybuilders intake a lot of proteins, prohormones and muscle building supplements to build bulk. This can cause strain on the liver. Liv-52 helps to remove toxic effects that such excess consumption can cause and maintains health of liver cells.

Can I take other herbal supplements while taking Liv-52?

Yes, Liv 52 is generally safe to take with other supplements. As a detoxifying agent, it is actually often recommended to be taken along with other supplements as it helps to improve their effects.

Is Liv-52 good for heavy drinkers?

Liv-52 helps to get rid of toxins produced from alcohol consumption. It can help to mitigate damage to the liver. If you are a heavy drinker it is best to stop or drastically reduce drinking in order to allow the liver to get detoxified and regenerate damaged cells.

Do I need to have a special diet if I am taking Liv-52?

No - there are no dietary restrictions while taking Liv 52. However if you wish to take Liv 52 in order to improve liver and kidney functions then it is best to also take foods that are beneficial for these organs. Avoid processed sugars, fatty foods, fried foods, processed foods. Foods that are good for fatty liver are raw vegetables, green leafy vegetables, sweet potatoes, bananas. Herbs like Karela, Turmeric, Ginger, Punarnava, Dandelion root, Milk thistle are also beneficial.

Will Liv-52 cause weight gain?

Liv 52 is not designed specifically to increase weight. If you are suffering from protein malnourishment or poor digestive issues Liv 52 will help in improving digestion and absorption. It will also help to improve appetite. This in turn can lead you to achieve a healthy normal weight.

Will Liv-52 cause weight loss?

No, Liv 52 will not cause weight loss. The herbs in Liv 52 promote cleansing of the digestive tract and colon. It also helps in scavenging and eliminating toxins. While doing so, it will help nutrients to be better absorbed.

Is it good to take Liv 52 with Purim?

Both Liv 52 and Purim are powerful detoxifying herbal blends. Purim is geared toward blood purification and in clearing skin conditions. It helps to maintain clear healthy skin. When Liv 52 and Purim are taken together you can achieve an optimal detoxification for your body as Liv 52 is primarily meant for the health of the liver and kidneys.

Can I take Liv 52 with Triphala?

Yes. Liv 52 and Triphala are a very good combination. Triphala is a well known detoxifier. It helps improve digestion and food absorption while cleansing the colon and removing toxins. It works well with Liv.52 for whole body detoxification.

Can I take allopathic medicines with Liv 52?

There are no known drug interactions of Liv 52 with allopathic medicines. In many cases Liv52 is advised to be taken along with medicines to mitigate the damage they can cause to the liver. However it is best to always check with your doctor if you can taken Liv 52 with the medicines you have been prescribed.

What is the difference between Liv 52 and Liv 52 DS?

Liv 52 DS stands for Liv 52 Double Strength. The ingredients in each tablet of Liv 52 are doubled in Liv 52 DS. However the number of tablets per bottle of Liv 52 is 100 whereas Liv 52 DS contains 60 tablets. The original formulation of Liv 52 is generally more widely taken as it is easier to control dosage.

Difference between Liv.52 and Liv.52 DS Infographic


Liv52 video on benefits, ingredients, dosage, side effects and drug interactions



Liv-52 slide presentation

References & Information on Liv52 obtained from:

1. Himalaya Herbals Company

2. Liv.52 regulates ethanol induced PPARgamma and TNF alpha expression in HepG2 cells.
Molecular and Cellular Biochemistry. 2008 May 1.
Mitra SK, Varma SR, Godavarthi A, Nandakumar KS.

3. Hepatoprotective effects of Liv-52 on ethanol induced liver damage in rats.
Indian Journal of Experimental Biology 1999 Aug;37(8):762-6. Department of Biochemistry, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

4. Advanced Pharmaceutical Bulletin 2017 Dec;7(4):645-650. doi: 10.15171/apb.2017.077. Epub 2017 Dec 31.
Effect of Daily Caper Fruit Pickle Consumption on Disease Regression in Patients with Non-Alcoholic Fatty Liver Disease: a Double-Blinded Randomized Clinical Trial.
Khavasi N, Somi MH, Khadem E, Faramarzi E, Ayati MH, Fazljou SMB, Torbati M.

5. Food and Chemical Toxicology: An international journal published for the British Industrial Biological Research Association. 2014 Oct;72:138-46. doi: 10.1016/j.fct.2014.06.029. Epub 2014 Jul 7.
Ameliorating effect of chicory (Chichorium intybus L.) fruit extract against 4-tert-octylphenol induced liver injury and oxidative stress in male rats.
Saggu S, Sakeran MI, Zidan N, Tousson E, Mohan A, Rehman H.

6. Indian Herbal Remedies: Rational Western Therapy, Ayurvedic and Other Traditional Usage, Botany
edited by C.P. Khare

7. Journal of Traditional and Complementary Medicine. 2015 Jan 22;6(2):160-7. doi: 10.1016/j.jtcme.2014.12.002. eCollection 2016 Apr.
Extract of a polyherbal formulation ameliorates experimental nonalcoholic steatohepatitis.
Azeemuddin M, Rafiq M, Anturlikar SD, Sharath Kumar LM, Patki PS, Babu UV, Shyam R.

8. Biological Trace Element Research. 2014 Sep;160(3):400-8. doi: 10.1007/s12011-014-9994-7. Epub 2014 Jul 13.
Hepatoprotective effects of Solanum nigrum Linn fruits against cadmium chloride toxicity in albino rats.
Abdel-Rahim EA, Abdel-Mobdy YE, Ali RF, Mahmoud HA.

9. Journal of Ethnopharmacology. 2014 Sep 11;155(2):1029-45. doi: 10.1016/j.jep.2014.06.056. Epub 2014 Jul 8.
Terminalia arjuna in coronary artery disease: ethnopharmacology, pre-clinical, clinical & safety evaluation.
Kapoor D, Vijayvergiya R, Dhawan V.

10. Asian Pacific Journal of Tropical Medicine. 2015 Sep;8(9):685-93. doi: 10.1016/j.apjtm.2015.07.030. Epub 2015 Aug 6.
Diuretic and antioxidant activities of the aqueous extract of leaves of Cassia occidentalis (Linn.) in rats.
Ntchapda F, Barama J, Kemeta Azambou DR, Etet PF, Dimo T.

11. Journal of Ethnopharmacology. 2013 Aug 26;149(1):157-61. doi: 10.1016/j.jep.2013.06.015. Epub 2013 Jun 18.
Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae).
de Souza P, Crestani S, da Silva Rde C, Gasparotto F, Kassuya CA, da Silva-Santos JE, Gasparotto A Jr.

12. Journal of Enzyme Inhibition and Medicinal Chemistry. 2006 Apr;21(2):215-23.
Tamarix gallica ameliorates thioacetamide-induced hepatic oxidative stress and hyperproliferative response in Wistar rats.
Sehrawat A, Sultana S.



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