Punarnava Facts:
Botanical Name : : Boerhavia Diffusa
Family Name: : Nyctaginaceae
Common Name: : Hog Weed, Spreading Hog Weed, Pig Weed, Horse Purslane, Tar Vine
Punarnava is a weed that grows in India. It is a creeping, spreading plant that grows upto 2 meters in length. It has pink flowers with green or brown oval fruits. Its roots, leaves and seeds are used for medicinal purposes.
Punarnava was observed by villagers to spring back to life after being a dead dry plant and hence its name the Renewer. Punarnava grows both in India as well as in Brazil where it is known as Erva tostao and is also used as a kidney and liver tonic.
Punarnava in Ayurveda:
As per ayurveda, punarnava's properties are bitter, cooling, astringent and purifying. Punarnava is said to balance all three doshas of vata, pitta and kapha. The roots are considered an excellent diuretic and it aids in preventing fluid retention in the body.
Directions for taking Punarnava
1 capsule twice a day before meals. Allow several weeks for long lasting benefits. Natural products treat not just the symptoms but the body as a whole and take time for absorption and results.
Pure Punarnava from Himalaya Herbals
Himalaya Punarnava is from the renowned Himalaya Herbals brand endorsed by over 250,000 doctors worldwide and used by customers in over 60 countries. Himalaya Herbals products have been researched clinically and standardized to guarantee bioequivalence. Bioequivalence refers to ensuring that the product on the market is equivalent to the one on which clinical trials were successfully conducted. Himalaya Herbal Healthcare uses chromatographic fingerprinting, one of the most sophisticated standardization techniques, to ensure consistent quality and performance
Research on Punarnava / Boerhaavia
Antifungal activity of Boerhavia diffusa against some dermatophytic species of Microsporum.
Hindustan Antibiot Bull. 2003 Feb-2004 Nov;45-46(1-4):1-4.
Various extracts petroleum ether, chloroform, ethyl acetate and ethyl alcohol) of aerial and root parts of Boerhavia diffusa was sereened for Antitungal activity (Inhibition in sporulation) against dermatophytic fungi Microsporum gypseum, M. fulvum and M. canis by using broth dilution method. Extracts of aerial part not show any noticeable antifungal activity. Ethyl acetate extract of root part of the plant was found to be most effective of against target fungal species. The maximum inhibition of mycelial growth was observed for M. gypseum (78.83%) followed by M. fulvum (62.33%) and M. canis (42.30%) of ethyl acetate in the test concentration of 1000 microg/ml 24 hours of incubation. The sporulation of target fungal species decreases with increasing supplementation of phytoextract, confirms the presence of some antifungal phytochemical moiety in roots of the plant.
Spasmolytic effects of nonprenylated rotenoid constituents of Boerhaavia diffusa roots.
J Nat Prod. 2006 Jun;69(6):903-6
Boerhaavia diffusa is an Ayurvedic remedy used traditionally for the treatment of a number of diseases, including those affecting the gastrointestinal tract. In the current investigation, a methanol extract obtained from roots of B. diffusa exhibited a significant spasmolytic activity in the guinea pig ileum, probably through a direct effect on the smooth muscle. A detailed phytochemical analysis of this methanol extract led to the isolation of one new (12) and six known (6-11) rotenoid derivatives. The structure of the new compound was determined through interpretation of its MS and NMR data. All the isolated rotenoids were evaluated for their effect on intestinal motility in vitro, and the results obtained showed unambiguously that they are active spasmolytic constituents. Preliminary structure-activity relationships for this class of compounds are suggested.
Isolation of new rotenoids from Boerhaavia diffusa and evaluation of their effect on intestinal motility.
Planta Med. 2005 Oct;71(10):928-32
A bioassay-guided separation of a methanolic extract obtained from the roots of Boerhaavia diffusa L. (Nyctaginaceae) allowed us to isolate five compounds belonging to the class of rotenoids: the known boeravinone D ( 1), boeravinone E ( 2), compound 5 and two novel compounds that we have named boeravinone G ( 3) and boeravinone H ( 4). The structures of the new molecules have been determined on the basis of their HR-EI-MS, (1)H- and (13)C-NMR and 2D-NMR (HMQC, HMBC) data. All the isolated rotenoids have been evaluated for their effect on intestinal motility in vitro. Three of them (boeravinone G, boeravinone E and compound 5) exhibited spasmolytic activity. Preliminary structure-activity relationships have been established highlighting the effect of substitutions on rings B and D.
References:
Himalaya Herbals Company
Pubmed
Other Products for Kidney & Liver