Himalaya Abana
Benefits of Abana : Cardio-protective, lowers cholesterol, lowers LDL, increases HDL, lowers blood pressure
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Abana from Himalaya Herbals is a herbal ayurvedic formulation. Abana has been formulated for optimum heart health. It helps to lower cholesterol and LDL while raising HDL. It works as a cardio-protective by improving the contractility of the heart and reducing sensitivity to adrenergic stimulation. It also reduces platelet aggregation.
Abana can be taken as a daily supplement to prevent heart attacks, reduce the risk factors of coronary heart disease, reduce hypertension as well as nervousness and anxiety. Abana does not cause any significant change in the blood pressure of normotensive individuals.
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Himalaya Abana
60 Tablets per Bottle
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3 Bottles
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6 Bottles
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12 Bottles
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Benefits of Abana
- Abana is a cardio-protective
- Abana helps reduce hypertension
- Abana helps in blood circulation
- Abana helps to reduce cholesterol and lower serum lipids
- Abana helps overcome nervousness and anxiety which leads to cardiac neurosis
Indications for taking Abana
Directions for taking Himalaya Abana
Generally 2-3 tablets, twice daily best taken with warm water. Please consult your physician to prescribe the dosage that best suits your condition. Natural products treat not just the symptoms but the body as a whole and take time for absorption and results.
Abana from Himalaya Herbals
Himalaya Abana is from the renowned Himalaya Herbals brand endorsed by over 250,000 doctors worldwide and used by customers in over 60 countries. Himalaya Herbals products have been researched clinically and standardized to guarantee bioequivalence. Bioequivalence refers to ensuring that the product on the market is equivalent to the one on which clinical trials were successfully conducted. Himalaya Herbal Healthcare uses chromatographic fingerprinting, one of the most sophisticated standardization techniques, to ensure consistent quality and performance
Abana ingredients and composition
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Arjuna (Terminalia arjuna) 30mg
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Ashvagandha (Withania somnifera) 20mg
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Badranj boya (Nepeta hindostana) 20mg
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Dashamoola 20mg
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Guduchi (Tinospora cordifolia) 10mg
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Amalaki (Emblica officinalis) 10mg
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Haritaki (Terminalia chebula) 10mg
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Bhringaraja (Eclipta alba Syn. E.prostrata)
10mg
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Yashti-madhu (Glycyrrhiza glabra)
10mg
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Shatavari (Asparagus racemosus) 10mg
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Punarnava (Boerhaavia diffusa) 10mg
Pdrs:
- Guggulu (Balsamodendron mukul Syn. Commiphora
wightii) (Purified) 30mg
- Shilajeet (Purified) 20mg
- Mandukaparni (Centella asiatica) 10mg
- Shankhapushpi (Convolvulus pluricaulis) 10mg
- Vishnu priya (Ocimum sanctum Syn.
O.tenuiflorum) 10mg
- Jatamansi (Nardostachys jatamansi) 10mg
- Pippali (Piper longum) 10mg
- Yavani (Carum copticum Syn. Trachyspermum ammi)
10mg
- Sunthi (Zingiber officinale) 10mg
- Nagapashana bhasma 10mg
- Shankh bhasma 10mg
- Makardhwaj 10mg
- Musta (Cyperus rotundus) 5mg
- Vacha (Acorus calamus) 5mg
- Vidanga (Embelia ribes) 5mg
- Lavanga (Syzygium aromaticum) 5mg
- Jyotishmati (Celastrus paniculatus) 5mg
- Chandana (Santalum album) 5mg
- Ela (Elettaria cardamomum) 5mg
- Shatapushpa (Foeniculum vulgare) 5mg
- Satapatrika (Rosa damascena Syn. R.centifolia)
5mg
- Tavak patra (Cinnamomum cassia) 5mg
- Abhrak bhasma 5mg
- Mukta pishti (Pearl pishti) 5mg
- Akik pishti (Agate pishti) 5mg
- Yeshab pishti (Vyomashma pishti) 5mg
- Yakut pishti (Manikya pishti) 5mg
- Praval pishti (Coral pishti) 5mg
- Kumkuma (Crocus sativus) 2mg
Abana Research and Clinical Studies
Double-blind comparative clinical trial of Abana and Simvastatin in Hyperlipidaemia
Venkataramaiah, H., M.D., D.M. (Cardiology), Professor of Cardiology, Jayadeva Institute of Cardiology, Jayanagar East End, Bangalore, India.
[Corresponding author: Kala Suhas Kulkarni, M.D., Medical Advisor, R&D Center, The Himalaya Drug Company, Makali, Bangalore, India]
INTRODUCTION
Observational studies have established hyperlipidaemia as an independent risk factor for coronary artery disease. It is now proved that hyperlipidaemia is an independent risk factor for ischemic stroke. Additional evidence from the prospective studies have shown the relationship between plasma cholesterol levels and risk of stroke. Reduction in the plasma cholesterol is accompanied by significant decrease in the incidence of coronary artery disease and stroke.
Data from individual randomised trials and meta-analyses of randomised trials consistently show a reduction in risk for both fatal and nonfatal coronary heart disease following primary and secondary prevention. A recent comprehensive overview by Law and colleagues incorporated data from 28 trials of cholesterol reduction, including 6 multiple intervention trials that each had a cholesterol-reducing arm. This overview indicated that a 10% reduction in serum cholesterol level resulted in highly significant reductions mortality from coronary heart disease. These data from randomised trials are consistent with observational data when treatment lasts 5 years or more. A 10% reduction in cholesterol levels was associated with a 25% reduction in coronary events among persons treated for more than 5 years. These findings from meta-analyses are also supported by recent reports from the Scandinavian study and the West of Scotland Coronary Prevention Study.
Herbs have been used since ancient times for reducing body lipids. Reports on all garlic studies performed, found cholesterol was lowered by an average of 9-12% over a one-to-four month period9. Guggul, a mixture of substances taken from the plant Commiphora mukul, is an approved treatment for elevated cholesterol in India and has been a mainstay of the Ayurvedic approach in preventing atherosclerosis. One trial studying the effects of guggul reported that serum cholesterol dropped by 17.5%10. In another report comparing guggul to the drug clofibrate, average fall in serum cholesterol was slightly greater in the guggul group while HDL cholesterol rose in 60% of people responding to guggul, while clofibrate treatment did not elevate HDL. Wild yam another herb commonly used has also been reported to raise HDL cholesterol in preliminary research12. With the above leads we planned a double-blind comparative clinical study using Abana and Simvastatin.
MATERIALS AND METHODS
Seventy patients were evaluated for general health and lipid profile through a medical history and a thorough physical examination. Patients with secondary hyperlipidaemia, alcoholism, or body weight more than 15% above the ideal for their height were excluded from the study. Baseline
cholesterol and triglycerides of estimation were carried out. The patients showing serum total cholesterol levels more than 200 mg/dL or serum triglyceride levels more than 200 mg/dL were included in the study.
After screening fifty patients qualified for the study, their ages ranged from 29 to 64 years, with a median of 46. There were 37 male and 13 female patients. Each patient underwent routine hematological and biochemical laboratory investigations. Patients were asked not to eat any food, except for water, for 12 to 14 hours before taking blood samples. Routine urine analysis and electrocardiography was also carried out. The study planned was double blind, randomized comparative study for 8 weeks. The written and informed consent was obtained from all the patients. Patients took 2 capsules of the drug before breakfast and at bedtime. The patients had to visit every 2 weeks for 8 weeks. A registered dietician interviewed the patients and instructed them to have diet with low cholesterol and saturated fats.
The clinical side effects if any were recorded at each visit and discussed with the patient to know the nature, severity and frequency. Patients were seen by the same dietician at every clinic visit throughout the study and were instructed to follow the same diets and to maintain weight, physical activity levels and smoking frequency for the duration of the study. To evaluate diet compliance, patients made written records of the quantity and type of food consumed in 4 consecutive days, including a weekend, between visits. These food diaries were kept on special forms that were then translated into computer language and analyzed by a program designed for that purpose. Patients reported their usual physical activity and smoking habits on a special card at every visit. All but three patients did not smoke cigarettes. Repeat laboratory investigations and electrocardiography were done after completion of the study.
Concomitant medications were monitored throughout the study. Twenty-three patients took no other drugs, 11 took asprin, acetaminophen, or both, 8 took antihistamines / antiallergic preparations, vitamins, or mineral supplements, 7 took minor tranquilizers, sedatives, or laxatives, 4 took nonsteroidal anti-inflammatory drugs, 4 took antacids or anticholinergic drugs, and 2 took antibiotics. The results were analyzed using paired ‘t’ test.
RESULTS
Of the 50 patients who entered the active-treatment phase of the study, 3 were excluded because of non-compliance. The patients followed fairly uniform dietary patterns during the trial and their compliance was assured by routine interviews with the dietician and review of the computer’s analysis of dietary records at every clinic visit. Routine follow-up by the dietician resulted in good overall dietary compliance and accounted for the attainment, in many patients of normal cholesterol levels in both the drug treatment. Results of those patients taking Abana showed a reduction of cholesterol from 215.3 ± 7.42 mg/dl to 192.3 ± 9.08 mg/dl. Reduction in cholesterol from 204.2 ± 8.43 to 157.0 ± 7.54 mg/dl occurred with Simvastatin. Triglycerides levels were also reduced from 216.0 ± 26.37 mg/dl to 187.7 ± 21.28 mg/dl and 214.7 ± 34.09 to 173.5 ± 23.23 mg/dl with Abana and Simvastatin respectively. In HDL, levels were increased in a similar fashion with Abana and Simvastatin treatment. Although, the rise in HDL cholesterol was similar in both the drugs, Simvastatin produced increase of HDL-cholesterol marginally higher than the Abana. However considering the risks involved in taking statin drugs, Abana is the safer alternative
References:
Himalaya Herbals Company
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